| 509 | 1 | 1 | TOP-M | DAN | Cleary | 41 | M | | 17:41.4 | 5:42 | 17:42.3 |
| 199 | 2 | 1 | M2029 | QUANGVINH | Tran | 21 | M | Team Nextpoint Therapeutics | 17:44.1 | 5:43 | 17:45.3 |
| 63 | 3 | 2 | M2029 | KYLE | Sutton | 25 | M | Olympus Tough Crew | 17:49.1 | 5:45 | 17:50.6 |
| 67 | 4 | 1 | M4049 | YOSHIKAZU | Tsugiyama | 48 | M | Olympus Tough Crew | 19:26.1 | 6:16 | 19:31.4 |
| 275 | 5 | 1 | M3039 | MICHAEL | Sage | 33 | M | Cologuardians Of The Galaxy | 20:28.4 | 6:36 | 20:31.0 |
| 196 | 6 | 2 | M3039 | EMILIEN | Lrd | 34 | M | Team Nextpoint Therapeutics | 21:12.8 | 6:50 | 21:21.9 |
| 519 | 7 | 3 | M2029 | DIMO | Dimitrov | 28 | M | | 21:19.4 | 6:52 | 21:21.6 |
| 318 | 8 | 1 | TOP-F | MARISSA | Devlin | 36 | F | Gambee | 21:25.8 | 6:54 | 21:28.5 |
| 458 | 9 | 4 | M2029 | ALEJANDRO | Smith | 28 | M | Team Takeda | 21:38.0 | 6:58 | 25:51.6 |
| 510 | 10 | 1 | F3039 | REBECCA | Cotugno | 37 | F | | 21:42.7 | 7:00 | 21:44.2 |
| 315 | 11 | 1 | M0115 | DANIEL | Roeder | 18 | M | Frolicking Foodies | 21:59.8 | 7:05 | 22:04.5 |
| 162 | 12 | 1 | M0110 | WREN | Firestone | 8 | M | Team Jeannine 5k4j | 22:35.6 | 7:17 | 24:28.5 |
| 84 | 13 | 2 | M0115 | MARK | McPherson | 18 | M | Pattie's Party Poopers | 22:36.5 | 7:17 | 22:37.3 |
| 276 | 14 | 3 | M3039 | NICOLAS | Sluyter-Beltrao | 30 | M | Cologuardians Of The Galaxy | 22:50.6 | 7:22 | 22:53.7 |
| 512 | 15 | 2 | M4049 | BEN | Davenny | 48 | M | | 23:12.8 | 7:29 | 23:19.7 |
| 441 | 16 | 2 | F3039 | NICOLE | Gampp | 30 | F | Team Compass Therapeutics | 23:17.3 | 7:30 | 23:43.3 |
| 595 | 17 | 0 | | RUNNER | Unknown | 0 | M | | 23:18.6 | 7:31 | 23:43.3 |
| 453 | 18 | 4 | M3039 | KARAN | Gupta | 36 | M | Team Takeda | 23:55.3 | 7:42 | 24:20.9 |
| 321 | 19 | 5 | M3039 | BEN | Steckler | 34 | M | Gambee | 23:55.8 | 7:43 | 23:59.2 |
| 274 | 20 | 3 | F3039 | NATALIE | McGuire | 31 | F | Cologuardians Of The Galaxy | 23:57.3 | 7:43 | 23:59.9 |
| 48 | 21 | 3 | M0115 | THOMAS | Fitzgerald | 16 | M | Olympus Tough Crew | 23:59.2 | 7:44 | 24:04.8 |
| 45 | 22 | 1 | F2029 | JULIA | Chun | 24 | F | Olympus Tough Crew | 24:04.9 | 7:46 | 26:11.7 |
| 19 | 23 | 6 | M3039 | MICHAEL | Dantona | 32 | M | Exact Sciences Boston | 24:24.4 | 7:52 | 24:52.0 |
| 577 | 24 | 1 | F1114 | MARY | Lea | 13 | F | Christine | 24:30.3 | 7:54 | 24:45.7 |
| 527 | 25 | 1 | F0115 | LILA | Johnson | 16 | F | | 24:33.1 | 7:55 | 24:36.2 |
| 532 | 26 | 2 | F0115 | KIKI | McGourty | 16 | F | | 24:33.2 | 7:55 | 24:36.5 |
| 376 | 27 | 2 | F2029 | EMILY | Stauble | 28 | F | Milligan's Warriors | 24:37.7 | 7:56 | 24:41.8 |
| 373 | 28 | 4 | F3039 | ANGELA | Clark | 35 | F | Milligan's Warriors | 24:38.0 | 7:56 | 24:42.0 |
| 264 | 29 | 1 | F4049 | HEATHER | Cyr | 43 | F | Christine & Co Against Colon C | 24:50.7 | 8:00 | 24:54.8 |
| 59 | 30 | 1 | M5059 | RICHARD | Reynolds | 59 | M | Olympus Tough Crew | 24:53.3 | 8:01 | 25:00.5 |
| 180 | 31 | 2 | M5059 | VINH | Nguyen | 51 | M | Team Jeannine 5k4j | 24:59.8 | 8:03 | 25:33.4 |
| 194 | 32 | 5 | M2029 | RIALE | Gilligan | 27 | M | Team Nextpoint Therapeutics | 25:04.6 | 8:05 | 25:21.1 |
| 309 | 33 | 1 | M1114 | GRAYSON | Kendziorski | 12 | M | Frolicking Foodies | 25:06.3 | 8:05 | 25:09.8 |
| 551 | 34 | 3 | F2029 | LEXI | Zubricki | 24 | F | | 25:07.3 | 8:06 | 25:10.3 |
| 197 | 35 | 3 | M4049 | MATT | Rausch | 43 | M | Team Nextpoint Therapeutics | 25:11.2 | 8:07 | 25:26.6 |
| 158 | 36 | 4 | M0115 | GRAHAM | Firestone | 17 | M | Team Jeannine 5k4j | 25:11.4 | 8:07 | 25:22.3 |
| 184 | 37 | 1 | F5059 | ANYA | Tchoudakova | 58 | F | Team Jeannine 5k4j | 25:14.6 | 8:08 | 26:57.2 |
| 308 | 38 | 3 | M5059 | CHARLES | Kendziorski | 53 | M | Frolicking Foodies | 25:14.8 | 8:08 | 25:19.0 |
| 313 | 39 | 2 | F1114 | CLARA | Pelton | 11 | F | Frolicking Foodies | 25:15.3 | 8:08 | 25:19.1 |
| 164 | 40 | 1 | M6069 | DONALD | Gillies | 60 | M | Team Jeannine 5k4j | 25:39.2 | 8:16 | 29:13.6 |
| 558 | 41 | 5 | M0115 | JOSH | Lombardo | 18 | M | Christine | 25:43.9 | 8:17 | 25:48.9 |
| 174 | 42 | 4 | M5059 | WEI | Li | 55 | M | Team Jeannine 5k4j | 25:46.9 | 8:18 | 33:26.3 |
| 13 | 43 | 5 | M5059 | EDWARD | Weatherhead | 51 | M | Bum Rushers | 25:48.2 | 8:19 | 26:14.8 |
| 576 | 44 | 0 | | RUNNER | Unknown | 0 | M | | 25:53.2 | 8:20 | 26:03.0 |
| 170 | 45 | 4 | F2029 | ANNA | Iskenderian | 24 | F | Team Jeannine 5k4j | 25:55.5 | 8:21 | 26:10.2 |
| 172 | 46 | 2 | M6069 | THOMAS | Klem | 60 | M | Team Jeannine 5k4j | 26:12.9 | 8:27 | 26:28.9 |
| 408 | 47 | 3 | F1114 | ALLIE | Lipiec | 14 | F | Shawnna's Squad | 26:20.1 | 8:29 | 26:41.3 |
| 400 | 48 | 5 | F3039 | ASHTON | Cetto | 37 | F | Shawnna's Squad | 26:21.7 | 8:30 | 26:43.0 |
| 62 | 49 | 6 | M5059 | DAVE | Stevens | 53 | M | Olympus Tough Crew | 26:41.6 | 8:36 | 26:50.3 |
| 370 | 50 | 6 | F3039 | SARAH | Teczar | 39 | F | Krys's Semicolon ;) | 26:41.7 | 8:36 | 26:46.8 |
| 262 | 51 | 2 | F4049 | TINA | Counihan | 48 | F | Christine & Co Against Colon C | 26:48.0 | 8:38 | 33:46.9 |
| 415 | 52 | 3 | F4049 | AMANDA | Lemieux | 40 | F | Snicker Bars & Unicorns | 26:53.3 | 8:40 | 27:08.1 |
| 58 | 53 | 5 | F2029 | SARA | Prendergast | 22 | F | Olympus Tough Crew | 26:58.6 | 8:41 | 29:05.0 |
| 391 | 54 | 4 | F1114 | LEAH | Ruffing | 13 | F | Pat's Pack | 27:00.6 | 8:42 | 27:13.8 |
| 392 | 55 | 2 | M1114 | REID | Ruffing | 11 | M | Pat's Pack | 27:05.2 | 8:44 | 27:16.3 |
| 388 | 56 | 4 | F4049 | COLLEEN | Ruffing | 45 | F | Pat's Pack | 27:07.7 | 8:44 | 27:20.9 |
| 495 | 57 | 7 | M3039 | RAMON | YniguezIII | 35 | M | The Rump Shakers | 27:15.6 | 8:47 | 27:15.6 |
| 492 | 58 | 5 | F4049 | LISA | Yniguez | 45 | F | The Rump Shakers | 27:15.6 | 8:47 | 27:15.6 |
| 187 | 59 | 6 | F4049 | JULIE | Zawacki-Lucci | 47 | F | Team Jeannine 5k4j | 27:18.2 | 8:48 | 27:38.4 |
| 88 | 60 | 4 | M4049 | ANDREW | Pratt | 41 | M | Pattie's Party Poopers | 27:19.1 | 8:48 | 28:29.4 |
| 393 | 61 | 5 | M4049 | RICH | Ruffing | 48 | M | Pat's Pack | 27:26.1 | 8:50 | 27:43.3 |
| 260 | 62 | 5 | F1114 | KELSEY | Counihan | 13 | F | Christine & Co Against Colon C | 27:28.1 | 8:51 | 34:29.5 |
| 273 | 63 | 7 | M5059 | SYDNEY | Sandford | 50 | M | Christine & Co Against Colon C | 27:47.8 | 8:57 | 28:18.5 |
| 272 | 64 | 7 | F4049 | KATHARINE | Maker | 43 | F | Christine & Co Against Colon C | 27:51.2 | 8:58 | 28:20.0 |
| 593 | 65 | 6 | M4049 | ADRIAN | Naranjo | 40 | M | Ridgewood Runners | 27:59.7 | 9:01 | 28:04.6 |
| 130 | 66 | 6 | M2029 | ISAAC | Seabrook | 26 | M | Strollin' For The Colon | 28:01.6 | 9:02 | 28:10.4 |
| 155 | 67 | 8 | M5059 | BRIAN | Dwyer | 51 | M | Team Jeannine 5k4j | 28:02.2 | 9:02 | 28:09.3 |
| 213 | 68 | 8 | M3039 | CHRIS | Kiernan | 33 | M | Anns Beating Hearts | 28:07.9 | 9:04 | 28:28.2 |
| 55 | 69 | 7 | M4049 | JOSH | Ortwein | 47 | M | Olympus Tough Crew | 28:08.4 | 9:04 | 28:12.6 |
| 390 | 70 | 8 | M4049 | KEVIN | Ruffing | 45 | M | Pat's Pack | 28:14.7 | 9:06 | 28:29.7 |
| 132 | 71 | 7 | M2029 | JUSTIN | Winn | 27 | M | Strollin' For The Colon | 28:15.9 | 9:06 | 28:16.9 |
| 127 | 72 | 8 | M2029 | ZIGGY | Ribetto | 25 | M | Strollin' For The Colon | 28:26.0 | 9:10 | 28:28.7 |
| 112 | 73 | 6 | F2029 | LILLY | Devitt | 24 | F | Strollin' For The Colon | 28:26.2 | 9:10 | 28:28.4 |
| 257 | 74 | 9 | M4049 | CASEY | Calderwood | 48 | M | Christine & Co Against Colon C | 28:29.3 | 9:11 | 28:33.4 |
| 469 | 75 | 10 | M4049 | COLIN | Whooten | 41 | M | Team Whooten | 28:38.9 | 9:14 | 32:33.7 |
| 470 | 76 | 7 | F3039 | RACHEL | Whooten | 38 | F | Team Whooten | 28:38.9 | 9:14 | 32:34.8 |
| 113 | 77 | 9 | M2029 | JARED | Downey | 24 | M | Strollin' For The Colon | 28:40.4 | 9:14 | 28:47.1 |
| 312 | 78 | 9 | M5059 | TIMOTHY | Lafleche | 53 | M | Frolicking Foodies | 28:41.8 | 9:15 | 29:01.7 |
| 277 | 79 | 11 | M4049 | MICHAEL | Thackrey | 47 | M | Cologuardians Of The Galaxy | 28:44.2 | 9:15 | 28:47.7 |
| 66 | 80 | 8 | F4049 | ENA | Tsugiyama | 44 | F | Olympus Tough Crew | 28:48.8 | 9:17 | 29:35.2 |
| 564 | 81 | 3 | F0115 | NIKKI | Bourque | 17 | F | Olympus Tough Crew | 28:54.8 | 9:19 | 29:00.9 |
| 409 | 82 | 9 | M3039 | CHRIS | Lipiec | 39 | M | Shawnna's Squad | 28:57.6 | 9:20 | 29:19.2 |
| 597 | 83 | 10 | M3039 | PMILIO | Cole | 34 | M | | 29:04.8 | 9:22 | 29:25.6 |
| 52 | 84 | 7 | F2029 | MADDY | Hornung | 24 | F | Olympus Tough Crew | 29:11.8 | 9:24 | 37:55.8 |
| 49 | 85 | 10 | M2029 | LUCAS | Gustavson | 24 | M | Olympus Tough Crew | 29:12.7 | 9:25 | 37:56.0 |
| 118 | 86 | 8 | F2029 | EMMA | Izydorczak | 23 | F | Strollin' For The Colon | 29:14.3 | 9:25 | 29:15.7 |
| 263 | 87 | 3 | M1114 | CHASE | Cyr | 13 | M | Christine & Co Against Colon C | 29:15.0 | 9:25 | 29:49.3 |
| 570 | 88 | 9 | F2029 | KAYLEE | Camara | 24 | F | Bidmc | 29:16.9 | 9:26 | 29:44.2 |
| 16 | 89 | 12 | M4049 | GREGORY | Youman | 49 | M | Bum Rushers | 29:29.0 | 9:30 | 29:53.8 |
| 450 | 90 | 13 | M4049 | KASI | Arunachalam | 44 | M | Team Takeda | 29:29.9 | 9:30 | 29:54.8 |
| 524 | 91 | 3 | M6069 | PAUL | Games | 65 | M | | 30:04.3 | 9:41 | 30:17.3 |
| 314 | 92 | 10 | M5059 | JOSEPH | Pelton | 54 | M | Frolicking Foodies | 30:05.0 | 9:41 | 30:15.3 |
| 542 | 93 | 10 | F2029 | MARLAINA | Stickney | 23 | F | | 30:05.8 | 9:42 | 30:28.2 |
| 47 | 94 | 11 | F2029 | BRITTANY | Felder | 27 | F | Olympus Tough Crew | 30:07.9 | 9:42 | 30:14.3 |
| 21 | 95 | 11 | M3039 | CODY | Fuller | 33 | M | Exact Sciences Boston | 30:20.2 | 9:46 | 30:59.3 |
| 427 | 96 | 8 | F3039 | ROXANNE | Sutocky | 36 | F | Snicker Bars & Unicorns | 30:22.8 | 9:47 | 30:58.1 |
| 82 | 97 | 11 | M2029 | ALEX | McPherson | 26 | M | Pattie's Party Poopers | 30:33.4 | 9:51 | 31:42.2 |
| 538 | 98 | 11 | M5059 | JOHN | Richerson | 50 | M | | 30:34.6 | 9:51 | 30:43.1 |
| 311 | 99 | 9 | F4049 | KAREN | Lafleche | 49 | F | Frolicking Foodies | 30:36.7 | 9:52 | 30:55.3 |
| 129 | 100 | 12 | M2029 | LOUIS | Sargent | 22 | M | Strollin' For The Colon | 30:40.1 | 9:53 | 30:42.4 |